Mercedes has confirmed that it will supply Manor Marussia with current-year power units from the start of the 2016 campaign.
Manor Marussia has used Ferrari's 2014 power unit this year but will switch to Mercedes for next season, joining Williams and Force India in being supplied by the Brixworth-based operation.
Mercedes is set to lose Lotus as a customer, with the outfit likely to be purchased and consequently supplied by Renault.
Manor Marussia will also receive suspension and transmission components from Williams, as part of the deal.
"I am delighted to announce our new power unit partnership with Mercedes-Benz for the 2016 season and beyond," said Manor Marussia team boss John Booth.
"Although there were many factors governing our selection of an engine partner to help power us towards our long-term ambitions, ultimately the strength of the Mercedes-Benz package speaks for itself.
"2015 has been a rebuilding year in every aspect of our operation. Although we have not been able to make the incremental strides in competitiveness that the team has enjoyed in previous seasons, we have put in place a strong foundation from which to progress.
"Together with the potential we are seeing with our 2016 car in the wind tunnel, the Mercedes-Benz power unit will assist our return to aggressive performance development with effect from next season."
Booth thanked current suppliers Ferrari for their work, believing that the outfit owes the Italian marque a huge amount of gratitude for supporting its return at the start of 2015.
"In 2014, together we shared in the momentous occasion of the team’s first points and in 2015 Ferrari supported us to a degree that was above and beyond the requirements of our partnership agreement," he said.
"Quite simply, we could not have returned to the grid without them pushing extremely hard to support the MR03B, at the same time as focusing on their own 2015 package."